In this module, the students will learn about normal cardiovascular, respiratory, renal, liver, haematological and immune physiology and function. This is followed by pathophysiological processes in these system that result from critical illness. Students will learn about body's response to common insults such as infection, trauma and surgery and how the immune system and cellular processes manage this in an adaptive and at times maladaptive ways. The concepts of shock, cellular dysoxia and genetic factors will also be discussed.

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