Browse Hierarchy EMS735P: Biocompatibility Evaluation for Clinical Innovation
This module will provide a comprehensive understanding of the concepts related to and underpinning biocompatibility. It will cover topics including proteins and protein adsorption, biomaterial- cell, blood and tissue interactions, Inflammation, wound healing, foreign body response, Toxicity, hypersensitivity and infection. The pre-clinical testing of biomaterials will be considered with respect to chemical exchange and degradation, cell response (proliferation vs differentiation), evaluation of material compatibility, evaluation of device functionality (biomechanics, remodelling/adaptation). The importance of the intelligent design of pre-clinical test regimes and unbiased critical analysis of test data to drive development and new innovation in biomaterials and medical device design will be emphasized through consideration of case study scenarios. Clinical trials and regulatory approval will also be discussed.
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