Browse Hierarchy CHE306U: Advanced Pharmaceutical Chemistry

This module is concerned with the principles of drug design, drug discovery and the relationship between the molecular structure of drugs and their biological activity. Topics to be covered include: how candidate drug structures are selected for synthesis, structure activity relationships, physico-chemical properties of compounds and how these may be employed to assist in the selection of drug candidates, organic synthetic methods that are of particular relevance to the preparation of drug-like molecules. The module will build upon the knowledge and understanding of pharmaceutical chemistry gained in CHE206, and examines applications of the drug discovery process by focusing on specific disease areas such as cancer, where concepts and methods of current therapies and the structures and mechanisms of action of chemotherapeutic agents are studied.